Levia.ee 60 Postitatud Juuli 8, 2018 Health impact of E-cigarettes: a prospective 3.5-year study of regular daily users who have never smoked Summary and Conclusions In a small sample of young-adult never-smoking, daily EC users who were carefully followed for approximately 3½ years, we found no decrements in spirometric indices, development of respiratory symptoms, changes in markers of lung inflammation in exhaled air or findings of early lung damage on HRCT, when compared with a carefully matched group of never-smoking non-EC users. Even the heaviest EC users failed to exhibit any evidence of emerging lung injury as reflected in these physiologic, clinical or inflammatory measures. Moreover, no changes were noted in blood pressure or heart rate. Since the EC users who we studied were never smokers, potential confounding by inhalation of combustion products of tobacco were obviated. While the sample size was small, the results of this study may provide some preliminary evidence that long-term use of ECs is unlikely to raise significant health concerns in relatively young users. Further studies in a larger sample of EC users with and without a history of tobacco smoking are warranted. Source - https://www.nature.com/articles/s41598-017-14043-2 Share this post Link to post Share on other sites